Pilot vagal nerve stimulation for RA: interesting with clinical and immunological response, but surgical complications and lack of imaging data as yet. Also 4x/day worse than daily: too often might breed resistance? Looking forward to seeing more #EULAR2019 LB0009 @RheumNow pic.twitter.com/VZCl0RBlbq
— David Liew (@drdavidliew) June 15, 2019
Vagal nerve stimulation for management of RA. Effective in refractory RA #EULAR2019 pic.twitter.com/petEUKty7v
— Dr. Dinesh Khanna (@sclerodermaUM) June 15, 2019
Can implanting vagal nerve stimulator in tough to treat RA pts work? Could theoretically decrease TNF. Small RCT. Maybe. Daily vagal stimulation May work in some. LB0009 #EULAR2019 @RheumNow pic.twitter.com/mqtcFCEie5
— Janet Pope (@Janetbirdope) June 15, 2019
Benefits of #physicalactivity in #rheumatoidarthritis
➡️Disease related outcomes
➡️Systemic outcomes
➡️Financial costsvia @NoreleeK #EULAR2019#Exercise #arthritis pic.twitter.com/5vnKaPdAQB
— Dr Ai Lyn Tan (@DrAiLynTan) June 13, 2019
Eular highlights. Unanswered questions. Need RCTs in severe RA with targeted DMARD + biological? Should we cycle JAKs – need RCT. ?change target in RA to reflect real disease activity- inflammation and consider PROs separately #EULAR2019 @RheumNow
— Janet Pope (@Janetbirdope) June 16, 2019
Eular highlights. Need to know if order of Rx of advanced therapies makes a long term difference in RA and PsA. ?better effectiveness or retention with one strategy vs another. ?too much drug cycling #EULAR2019 @RheumNow
— Janet Pope (@Janetbirdope) June 16, 2019
Pts with RA have shame and guilt which correlates with demographics and disease activity. Something to think about, acknowledge and give proper help. FRI0030 #EULAR2019 @RheumNow
— Janet Pope (@Janetbirdope) June 15, 2019
Low dose steroids in RA are benign? I speak to @dr_rachelblack about cataract and glaucoma risk from steroids for @RheumNow (data from SAT0592 at #EULAR2019) https://t.co/3Qo4dZdTNK pic.twitter.com/1kLQ2VwSD3
— David Liew (@drdavidliew) June 15, 2019
You can stop MTX in RA pts in low disease state after adding tofa 11 mg daily long acting for 24 Wks if CDAI <11 (Oral Shift) No diff btw continue vs D/C MTX. Some pts will be happy to stop MTX without loss of effect LBOOO4 #EULAR2019 @RheumNow
— Janet Pope (@Janetbirdope) June 15, 2019
What happens when you use very low doses for rituximab retreatment for RA? More flares, but interesting mean disease activity/B cells comparison suggest most get by fine and fewer get infections #EULAR2019 LB0010 from Nijmegen @RheumNow pic.twitter.com/opsUMPwOFd
— David Liew (@drdavidliew) June 15, 2019
RA confers a similar risk of inpatient admission for influenza as age >65yo in a large Australian general medical cohort. When will our RA patients get similar access to high dose influenza vaccine as patients >65yo do? #EULAR2019 FRI0058 @bonnialiu @earlyARA @RheumNow pic.twitter.com/hR1fYHdZzQ
— David Liew (@drdavidliew) June 15, 2019
Good lessons from 22,607 RA patients from the UK CPRD: cataracts and glaucoma from pred are dose dependent, and even 1000mg cumulative dose is enough. That’s equivalent to three months PMR therapy for most #EULAR2019 SAT0592 @dr_rachelblack @CatherineL_Hill @earlyARA @RheumNow pic.twitter.com/AJfBgLdHdb
— David Liew (@drdavidliew) June 15, 2019
Does Rheumatoid Arthritis Really Improve During Pregnancy? A Systematic Review and Metaanalysis 👉🏻Disease activity improved in 60% of patients with RA in pregnancy and flared in 46.7% postpartum. https://t.co/QKun6vOzDY #EULAR2019 Thanks @montesa_maria pic.twitter.com/9QA84ITapO
— Carlo V Caballero MD (@carvicab) June 15, 2019
Association between pre-treatment ANA and TNFi immunogenicity in RA? Very interesting, worth exploring… #EULAR2019 SAT0155 from Shinko, Kobe, Japan @RheumNow pic.twitter.com/hmUNonteq4
— David Liew (@drdavidliew) June 15, 2019
Filgotinib effective in RA naive to MTX, either with or without MTX #EULAR2019 @RheumNow pic.twitter.com/HPTIG3e2Tp
— Emilio Martin Mola (@emartinmola) June 15, 2019
Checklists for RA patient ‘screening’: bad. How useful is a routine ANA, even for early RA assessment? This is what happens when you do it on every patient in an early RA clinic… whole lotta false positives. #EULAR2019 OP0323 Mariana Luis from Coimbra, Portugal @RheumNow pic.twitter.com/wa8PzVbais
— David Liew (@drdavidliew) June 14, 2019
This graph is a reminder that over time, the level of Inflammation in RA may reduce with lower symptoms. However, CUMULATIVE inflam leads to increasing damage & disability #EULAR2019 pic.twitter.com/ujhODMOp4E
— Dr Irwin Lim (@_connectedcare) June 14, 2019
Risk factors for #sarcopenia in #rheumatoid arthritis
👉🏼Male
👉🏼Old age
👉🏼Glucocorticoid
👉🏼Increased MMP3
👉🏼Increased HAQ#EULAR2019 THU0159#muscle #RheumatoidArthritis pic.twitter.com/Fn1SvCapqm— Dr Ai Lyn Tan (@DrAiLynTan) June 14, 2019
Remission in RA. Food for thought from Dr Aletaha. #eular2019 pic.twitter.com/5h6vUvGCDq
— Francisca Sivera (@FranciscaSivera) June 14, 2019
Could the gender of your physician make a difference? A study presented at #Eular2019 found female docs scored #RA patients higher for global health status and disease activity than male docs did, particularly among female patients @CreakyJoints pic.twitter.com/IAIbTubvxL
— Kelly Gavigan (@KellyLGav) June 14, 2019
Fertility is RA: strong data reminding us that active disease impairs fertility #eular2019 pic.twitter.com/gt0feJZaow
— Dr Irwin Lim (@_connectedcare) June 14, 2019
Almost a 50% of RA women will not improve during pregnancy and rates increases up to 70% in AS. So be aware that meds will be necessary in many pregnant women. Nelson-Piercy at Win&Hot session #EULAR2019 @RheumNow
— Emilio Martin Mola (@emartinmola) June 14, 2019
42% of early RA patients in Canadian CATCH cohort had prior inflamm joint palindromic-type symptoms (that ‘come and go’) and this subgroup had some interesting associations… #EULAR2019 FRI0065 @RheumNow @Janetbirdope pic.twitter.com/tcjzObIfsB
— David Liew (@drdavidliew) June 14, 2019
Is there added value of antiCarP for RA dx? THU0139. Think of ACPA as citrullination vs CarP -carbamyllation Don't know if added value for dx but CarP equally + at nearly half in ACPA + &- so could it replace ACPA and use it with RF #EULAR2019 @RheumNow pic.twitter.com/M7PfRysLel
— Janet Pope (@Janetbirdope) June 14, 2019
OPO315 ERA cohort shows fatigue improvement lags behind remission by 6 months. #EULAR2019 @RheumNow pic.twitter.com/6toBquAy2Q
— Janet Pope (@Janetbirdope) June 13, 2019